
Former President Joe Biden, 82, has been diagnosed with an aggressive form of prostate cancer characterized by a Gleason score of 9 and bone metastasis, presenting significant treatment challenges for the oldest person to have ever served as U.S. President.
Key Takeaways
- Biden has been diagnosed with Grade Group 5 prostate cancer (Gleason score 9) with metastasis to the bone, indicating an advanced and aggressive form of the disease.
- The cancer is hormone-sensitive, which offers potential treatment pathways currently being reviewed by Biden and his family.
- The diagnosis was made on May 16 after Biden experienced increasing urinary symptoms and follows his previous history of non-melanoma skin cancers.
- President Trump, former Vice President Harris, and other political figures across party lines have offered support and prayers for Biden’s recovery.
- Surgery is typically not an option when prostate cancer has spread to the bone, with hormone therapy being the likely treatment approach.
Biden’s Aggressive Cancer Diagnosis
The statement released on May 18 from former President Joe Biden’s office revealed his diagnosis with an advanced and aggressive form of prostate cancer. Medical evaluations conducted on May 16 detected a Gleason score of 9, placing it in Grade Group 5, the most serious classification for prostate cancer. The diagnosis followed the discovery of a small nodule in Biden’s prostate during a routine physical examination, which led to further testing that unfortunately confirmed bone metastasis, indicating the cancer has already spread beyond the prostate gland. This development marks a serious health challenge for the 82-year-old former president, who left office less than four months ago.
Despite the severity of the diagnosis, medical reports indicate that Biden’s cancer remains hormone-sensitive, which provides some treatment options. The Biden family is currently reviewing these options with medical professionals. Prostate cancer is the most common cancer among American men and the second leading cause of cancer death in this demographic. According to statistics, approximately 313,780 new cases of prostate cancer will be diagnosed in 2023, with an estimated 35,770 deaths expected. While the overall five-year survival rate for prostate cancer is 98%, this rate decreases significantly for cases with metastasis.
We are deeply saddened to learn Former President Joe Biden has been diagnosed with an aggressive form of prostate cancer. Our thoughts and well wishes for strength and healing are with the Biden family as they navigate this incredibly difficult time.
According to a statement… pic.twitter.com/uWME49BmOH
— ZERO Prostate Cancer (@ZEROCancer) May 18, 2025
National Response and Support
The announcement of Biden’s cancer diagnosis has prompted an outpouring of support from across the political spectrum. President Donald Trump and First Lady Melania expressed their concern and well-wishes for Biden’s recovery. Melania and I are saddened to hear about Joe Biden’s recent medical diagnosis. We extend our warmest and best wishes to Jill and the family, and we wish Joe a fast and successful recovery, said President Donald Trump. This gesture highlights how serious health challenges can transcend political divisions, even in our currently polarized political climate.
“Doug and I are saddened to learn of President Biden’s prostate cancer diagnosis. We are keeping him, former First Lady Dr. Jill Biden, and their entire family in our hearts and prayers during this time. Joe is a fighter—and I know he will face this challenge with the same strength, resilience, and optimism that have always defined his life and leadership. We are hopeful for a full and speedy recovery.” said Former Vice President Kamala Harris.
Other political figures, including Republicans, have also offered their support and prayers for Biden and his family during this difficult time. Representative Marjorie Taylor Greene joined many colleagues in expressing condolences and prayers. This unified response demonstrates that when facing serious health challenges, Americans can still come together with compassion despite their political differences. The diagnosis comes after a contentious election cycle where concerns about Biden’s age and health were frequently raised, making the timing particularly poignant for many observers.
“Dana-Farber Cancer Institute extends our support to Former President Joe Biden and his family following news of his diagnosis with aggressive, late-stage prostate cancer. His openness brings important attention to a growing public health concern, as cases of advanced prostate… pic.twitter.com/OU1C60y9ZF
— Dana-Farber (@DanaFarber) May 18, 2025
Treatment Options and Medical Context
For a patient with Biden’s diagnosis—advanced prostate cancer with bone metastasis—treatment options are somewhat limited but still offer hope for managing the disease. Surgery is typically not recommended once the cancer has spread to the bone. Instead, Androgen Deprivation Therapy (ADT), also known as hormone therapy, is likely to be the primary treatment approach. This therapy works by reducing levels of male hormones that fuel prostate cancer growth. The fact that Biden’s cancer is hormone-sensitive is a positive factor that may improve his response to this treatment.
“First Lady Melania and I are saddened to hear about Joe Biden’s recent medical diagnosis. We extend our warmest and best wishes to Jill and the family, and we wish Joe a fast and successful recovery.” said President Donald Trump.
Biden’s previous health history includes having a cancerous lesion removed from his chest in February 2023 and several non-melanoma skin cancers removed before he entered office. The American Cancer Society has expressed concern about the increasing number of advanced prostate cancer diagnoses in recent years, emphasizing the importance of early detection through regular screening. For men in Biden’s age group, managing aggressive prostate cancer presents particular challenges that require careful consideration of quality of life alongside treatment efficacy. The society continues to provide resources and support through their helpline and website for those facing similar diagnoses.